HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → 3-(Chloromethyl)-1,1'-biphenyl
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 3-Biphenylmethanol | HCID 603556 | — |
| Product | 3-(Chloromethyl)-1,1'-biphenyl | HCID 15480892 | — |
Reaction Steps
A solution of 50 mg of 3-hydroxymethylbiphenyl in 1.5 mL thionyl chloride was heated at reflux temperature for 4 hr, cooled to room temperature and the solvent removed by evaporation under reduced pressure to yield 45 mg of 3-chloromethylbiphenyl which was used in the next step without further purification or characterization.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06221871B1 |
| Source dataset | uspto-grants-2001_04 |
| ORD ID | ord-9e13e4c29c3e404eb17e55021b1c95f0 |
| Source note | uspto-grants-2001_04 |