HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzylamine → N-Benzyl-2-chloro-9-isopropyl-9H-purin-6-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzylamine | HCID 7504 | — |
| Reactant | 2,6-dichloro-9-(propan-2-yl)-9H-purine | HCID 11218490 | — |
| Solvent | 1-Butanol | HCID 263 | — |
| Product | N-Benzyl-2-chloro-9-isopropyl-9H-purin-6-amine | HCID 10733091 | 85% |
Reaction Steps
2,6-dichloro-9-isopropylpurine (1 mmol) and benzylamine (3,5 mmol) were heated with stirring in 3 ml of n-butanol (3 hour, 110° C.). The reaction mixture (after evaporation of n-butanol) was worked up as above for the compound 2, yield 85-90%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06221873B1 |
| Source dataset | uspto-grants-2001_04 |
| ORD ID | ord-ac9cf80d86554577856267a8dbe0d929 |
| Source note | uspto-grants-2001_04 |