6-Amino-1,3-dibutyl-5-nitroso-2,4(1H,3H)-pyrimidinedione → 5,6-Diaminouracil

Participants

Reaction Steps

15.0 g (52.8 mmol) 6-amino-1,3-di-n-butyl-5-nitrosouracil, 1.5 g 10% Pd/C and 150 mL DMF were hydrogenated at 40 psi in a Parr shaker for 4 h. After completion, the reaction mixture was filtered through Celite, and evaporated to give crude 5,6-diaminouracil as a dark oil.

Provenance & Evidence