Formaldehyde → HCID 22001680, compound

Participants

Reaction Steps

1.71 g (6.1 mmol) of 8-benzoyl-8-azabicyclo[3.2.1]octane-3-methanamine hydrochloride, 0.2 g (6.3 mmol) of paraformaldehyde and a few drops of concentrated hydrochloric acid in 10 ml of 2-propanol are introduced into a three-necked round-bottomed flask, the mixture is refluxed for 5 min, 0.78 g (5.3 mmol) of 2,3-dihydro-4H-1-benzopyran-4-one dissolved in 10 ml of 2-propanol is added and refluxing is continued for 18 h.

Provenance & Evidence