Cyclopentylamine → N-cyclopentyl-3-dimethylamino-1,2,3,4-tetrahydro-9H-carbazole-6-carboxamide

HRID 324997Notes

Reaction equation

[CH3:1][N:2]([CH3:19])[CH:3]1[CH2:15][C:14]2[C:13]3[C:8](=[CH:9][CH:10]=[C:11]([C:16]([OH:18])=O)[CH:12]=3)[NH:7][C:6]=2[CH2:5][CH2:4]1.[CH:20]1([NH2:25])[CH2:24][CH2:23][CH2:22][CH2:21]1>>[CH:20]1([NH:25][C:16]([C:11]2[CH:12]=[C:13]3[C:8](=[CH:9][CH:10]=2)[NH:7][C:6]2[CH2:5][CH2:4][CH:3]([N:2]([CH3:1])[CH3:19])[CH2:15][C:14]3=2)=[O:18])[CH2:24][CH2:23][CH2:22][CH2:21]1

Participants

Reactant 2

HCID 2906Cyclopentylamine

HCID 123618113-(Dimethylamino)-2,3,4,9-tetrahydro-1H-carbazole-6-carboxylic acid

Product 1

HCID 15512578N-cyclopentyl-3-dimethylamino-1,2,3,4-tetrahydro-9H-carbazole-6-carboxamideYield 41%

Procedure

Beginning with 7.4 mg (0.029 mMol) 3-dimethylamino-1,2,3,4-tetrahydro-9H-carbazole-6-carboxylic acid and cyclopentylamine, 4.1 mg (41%) of the title compound were recovered.

Sources & evidence

ORD record: ord-5726dad07e6a4f599a49a6ed2d851c54
Source dataset: uspto-grants-2001_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06221884B1

Reaction notes

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