4-(Chlorosulfonyl)-2-hydroxybenzoic acid → HCID 10651932, compound

HRID 325012Notes

Reaction equation

HRID 325012 reaction equation
[C:1]([C:9]1[O:10][C:11]2[CH:35]=[CH:34][CH:33]=[CH:32][C:12]=2[C:13]=1[C:14]1[CH:19]=[CH:18][C:17]([C:20]2[CH:25]=[CH:24][C:23]([OH:26])=[C:22]([CH:27]3[CH2:31][CH2:30][CH2:29][CH2:28]3)[CH:21]=2)=[CH:16][CH:15]=1)(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.Cl[S:37]([C:40]1[CH:48]=[CH:47][C:43]([C:44]([OH:46])=[O:45])=[C:42]([OH:49])[CH:41]=1)(=[O:39])=[O:38]>>[C:1]([C:9]1[O:10][C:11]2[CH:35]=[CH:34][CH:33]=[CH:32][C:12]=2[C:13]=1[C:14]1[CH:15]=[CH:16][C:17]([C:20]2[CH:25]=[CH:24][C:23]([O:26][S:37]([C:40]3[CH:48]=[CH:47][C:43]([C:44]([OH:46])=[O:45])=[C:42]([OH:49])[CH:41]=3)(=[O:39])=[O:38])=[C:22]([CH:27]3[CH2:28][CH2:29][CH2:30][CH2:31]3)[CH:21]=2)=[CH:18][CH:19]=1)(=[O:8])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 146685314-(Chlorosulfonyl)-2-hydroxybenzoic acidHCID 18360817HCID 18360817, compound

Product 1

HCID 10651932HCID 10651932, compound

Procedure

The title compound was prepared from 4′-(2-benzoyl-benzofuran-3-yl)-3-cyclopentyl-biphenyl-4-ol and 4-chlorosulfonyl-2-hydroxy-benzoic acid, in substantially the same manner, as described in Example 1 step g, and was obtained as a yellow solid, mp 105-108° C.; MS m/e 694 (M-H)+;

Workup

  1. customwas obtained as a yellow solid, mp 105-108° C.

Sources & evidence

ORD record
ord-08b0ee2e41d942169edcbc79a6103632
Source dataset
uspto-grants-2001_04
Patent number
US06221902B1

Reaction notes

Loading…