Cyclopropanemethanamine → 2-Aminopyrimidine-4-carboxaldehyde (cyclopropylmethyl)imine

HRID 325105Notes

Reaction equation

[NH2:1][C:2]1[N:7]=[C:6]([CH:8]=O)[CH:5]=[CH:4][N:3]=1.[CH2:10]1[CH2:12][CH:11]1[CH2:13][NH2:14]>>[CH:11]1([CH2:13][N:14]=[CH:8][C:6]2[CH:5]=[CH:4][N:3]=[C:2]([NH2:1])[N:7]=2)[CH2:12][CH2:10]1

Participants

Reactant 2

HCID 75646Cyclopropanemethanamine

HCID 178323462-Aminopyrimidine-4-carbaldehyde

Product 1

HCID 861821762-Aminopyrimidine-4-carboxaldehyde (cyclopropylmethyl)imine

Procedure

2-Aminopyrimidine-4-carboxaldehyde and 2-cyclopropylmethyl amine were reacted by the procedure of example 1(c) to afford the title compound as a yellow oil.

Sources & evidence

ORD record: ord-cda45f10c3a24c18a42145d3c8c06979
Source dataset: uspto-grants-2001_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06222036B1

Reaction notes

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