Cyclopropanemethanamine → 2-Methylpyridine-4-carboxaldehyde(Cyclopropylmethyl)imine

HRID 325110Notes

Reaction equation

[CH:1]([C:3]1[CH:8]=[CH:7][N:6]=[C:5]([CH3:9])[CH:4]=1)=O.[CH:10]1([CH2:13][NH2:14])[CH2:12][CH2:11]1>>[CH:10]1([CH2:13][N:14]=[CH:1][C:3]2[CH:8]=[CH:7][N:6]=[C:5]([CH3:9])[CH:4]=2)[CH2:12][CH2:11]1

Participants

Reactant 2

HCID 75646Cyclopropanemethanamine

HCID 27630002-METHYLISONICOTINALDEHYDE

Product 1

HCID 861820892-Methylpyridine-4-carboxaldehyde(Cyclopropylmethyl)imine

Procedure

Reaction of 4-formyl-2-methylpyridine [prepared in Example 33(a)] and cyclopropylmethyl amine by the procedure of example 1(c) affords the title compound as a yellow oil.

Sources & evidence

ORD record: ord-3f50ad56d3f34dc2a81732b478bedec7
Source dataset: uspto-grants-2001_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06222036B1

Reaction notes

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