反应详情

180 g of o-(chloromethyl)benzoyl chloride was placed in a double-neck 500 ml flask equipped with a thermometer, cooler and dropping funnel. While maintaining the internal temperature of a reactor at 40˜50° C., 50 ml of methanol was added dropwise. After all amounts of methanol were infused, the reacting mixture was stirred for 10 hours, while maintaining the internal temperature of a reactor at 40˜50° C. After a distillator was equipped, a fractional distillation under reduced pressure was made to afford 165 g of desired compound (yield 94%) as oil.

1. customequipped with a thermometer, cooler
2. temperatureWhile maintaining the internal temperature of a reactor at 40˜50° C.
3. temperaturewhile maintaining the internal temperature of a reactor at 40˜50° C
4. customAfter a distillator was equipped
5. distillationa fractional distillation under reduced pressure