Ethyl 2-[(4-hydroxyphenyl)methylene]-3-oxobutanoate → HCID 12657785, compound

HRID 325128Notes

Reaction equation

HRID 325128 reaction equation
[CH2:1]([O:3][C:4](=[O:17])[C:5]([C:14](=[O:16])[CH3:15])=[CH:6][C:7]1[CH:12]=[CH:11][C:10]([OH:13])=[CH:9][CH:8]=1)[CH3:2].[H][H]>[Ni]>[CH2:1]([O:3][C:4](=[O:17])[CH:5]([CH2:6][C:7]1[CH:12]=[CH:11][C:10]([OH:13])=[CH:9][CH:8]=1)[C:14](=[O:16])[CH3:15])[CH3:2]

Participants

4

Reactant 2

HCID 878668Ethyl 2-[(4-hydroxyphenyl)methylene]-3-oxobutanoateHCID 178418361HCID 178418361, compound

Product 1

HCID 12657785HCID 12657785, compound

Reagents, catalysts & solvents 1

HCID 935NickelCatalyst

Procedure

According to the procedure of Liebigs Ann. Chem. (1980), 9, 1392, 2-(4-hydroxy-benzyl)-3-oxo-butyric acid ethyl ester was prepared from 2-acetyl-3-(4-hydroxy-phenyl)-acrylic acid ethyl ester, Raney-nickel, hydrogen.

Sources & evidence

ORD record
ord-500b5c2382654f36ad52f8cfda2f2862
Source dataset
uspto-grants-2001_04
Patent number
US06222062B1

Reaction notes

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