Styrene → 220751-29-1

HRID 325139Notes

Reaction equation

HRID 325139 reaction equation
[F:1][C:2]1[CH:8]=[CH:7][C:5]([NH2:6])=[CH:4][CH:3]=1.[CH2:9]=[CH:10][C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1>C(OCC)(=O)C.CCCCCC>[C:11]1([CH2:10][CH2:9][NH:6][C:5]2[CH:7]=[CH:8][C:2]([F:1])=[CH:3][CH:4]=2)[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1

Participants

4

Reactant 2

HCID 7501StyreneHCID 97314-Fluoroaniline

Product 1

HCID 9859205220751-29-1Yield 84%

Reagents, catalysts & solvents 1

HCID 21226206Ethyl acetate hexaneSolvent

Procedure

According to GWM, 0.011 mol (=1.10 ml) of p-fluoroaniline and 0.011 mol (=1.25 ml) of styrene are reacted with one another. The product is isolated by column chromatography using ethyl acetate/n-hexane (1:1) as eluent, the product N-(2-phenylethyl)-(p-fluoro)aniline being obtained as brown liquid.

Workup

  1. customare reacted with one another
  2. customThe product is isolated by column chromatography

Sources & evidence

ORD record
ord-a0eb3e4850dc465d826d1043f2846be6
Source dataset
uspto-grants-2001_04
Patent number
US06222073B1

Reaction notes

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