2-Chloro-N,N-dimethylethylamine → HCID 9803568, compound
Reaction equation
[CH3:1][N:2]([CH2:4][CH2:5]Cl)[CH3:3].[CH3:7][O:8][C:9]1[CH:14]=[CH:13][C:12]([C:15]2[O:16][C:17]3[CH:32]=[C:31]([O:33][CH3:34])[CH:30]=[CH:29][C:18]=3[C:19]=2[C:20](=[O:28])[C:21]2[CH:26]=[CH:25][C:24]([OH:27])=[CH:23][CH:22]=2)=[CH:11][CH:10]=1>>[CH3:7][O:8][C:9]1[CH:14]=[CH:13][C:12]([C:15]2[O:16][C:17]3[CH:32]=[C:31]([O:33][CH3:34])[CH:30]=[CH:29][C:18]=3[C:19]=2[C:20](=[O:28])[C:21]2[CH:26]=[CH:25][C:24]([O:27][CH2:5][CH2:4][N:2]([CH3:3])[CH3:1])=[CH:23][CH:22]=2)=[CH:11][CH:10]=1Participants
3
Procedure
The title compound was prepared essentially as described in Example 24, supra, except that 2-(N,N-dimethylamino)ethyl chloride was reacted with 2-(4-methoxyphenyl)-3-(4-hydroxybenzoyl)-6-methoxybenzofuran instead of the 2-(N,N-diisopropylamino)ethyl chloride employed in that example.
Sources & evidence
- ORD record
- ord-e37c8b260ebe4c20bd9a9b09183aaeed
- Source dataset
- uspto-grants-2001_04
- Patent number
- US06221838B1
Reaction notes
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