[1,1'-Biphenyl]-4-carboxylic acid, 4'-nitro- → 4'-Amino[1,1'-biphenyl]-4-carboxylic acid

HRID 325200Notes

Reaction equation

HRID 325200 reaction equation
[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([C:10]2[CH:15]=[CH:14][C:13]([C:16]([OH:18])=[O:17])=[CH:12][CH:11]=2)=[CH:6][CH:5]=1)([O-])=O>[Pd]>[NH2:1][C:4]1[CH:5]=[CH:6][C:7]([C:10]2[CH:15]=[CH:14][C:13]([C:16]([OH:18])=[O:17])=[CH:12][CH:11]=2)=[CH:8][CH:9]=1

Participants

3

Reactant 1

HCID 66723[1,1'-Biphenyl]-4-carboxylic acid, 4'-nitro-

Product 1

HCID 3086784'-Amino[1,1'-biphenyl]-4-carboxylic acid

Reagents, catalysts & solvents 1

HCID 23938PalladiumCatalyst

Procedure

The title compound can be prepared by palladium catalyzed hydrogenation of 4-nitro-4′-biphenyl carboxylic acid.

Sources & evidence

ORD record
ord-d6fb09667b5448b1b11e5ab93f041eec
Source dataset
uspto-grants-2001_04
Patent number
US06221865B1

Reaction notes

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