反应详情

A solution of the resultant ester from Example 6B (1.0 equivalent) in aqueous methanol is treated with NaOH (2.0 equivalents) and stirred until the reaction is deemed complete by TLC analysis. The mixture is acidified, diluted with water, and extracted into ethyl acetate which is dried and evaporated. Chromatography on silica gel provides the tide product.

1. extractionextracted into ethyl acetate which
2. customis dried
3. customevaporated
4. customChromatography on silica gel provides the tide product