HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methylamine → N-[4-(methylthio)thieno[2,3-d]pyrimidin-6-ylmethylidene]methanamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methylamine | HCID 6329 | — |
| Reactant | N-(3,4-dimethoxybenzyl)-N-[thieno[2,3-d]pyrimidin-6-ylmethylidene]amine | HCID 17965764 | — |
| Reactant | Thieno[2,3-d]pyrimidine-6-carbaldehyde | HCID 17965793 | — |
| Reactant | 4-(Methylthio)thieno[2,3-d]pyrimidine-6-carbaldehyde | HCID 17965859 | — |
| Product | N-[4-(methylthio)thieno[2,3-d]pyrimidin-6-ylmethylidene]methanamine | HCID 69059019 | — |
Reaction Steps
The title compound was prepared by a similar process to that described for Intermediate 14 but using 4-(methylthio)thieno[2,3-d]pyrimidine-6-carbaldehyde (Intermediate 15) in place of thieno[2,3-d]pyrimidine-6-carbaldehyde (intermediate 13) and methylamine (33% in methylated spirits) in place of 3,4-dimethoxybenzylamine. Colourless solid (73 mg, 98%);
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07427616B2 |
| Source dataset | uspto-grants-2008_09 |
| ORD ID | ord-c99c30271d41447d99271ac7db44687b |
| Source note | uspto-grants-2008_09 |