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HRID325244

反应详情

EQUATION

反应方程式

HRID 325244 的结构方程式

REACTANTS

反应物

2
结构：Oc1ccccc1
HCID996

Phenol

C6H6O

结构：CC(C)(C)OC(=O)N1CCCC1CO
HCID550865

tert-Butyl 2-(hydroxymethyl)pyrrolidine-1-carboxylate

C10H19NO3

PRODUCTS

生成物

1
结构：CC(C)(C)OC(=O)N1CCC[C@H]1COc1ccccc1
HCID10636271

(S)-tert-Butyl 2-(phenoxymethyl)pyrrolidine-1-carboxylate

C16H23NO3

收率 89.2%

PROCEDURE

实验过程

Following the procedure of example 1115 A, N-t-butoxycarbonyl-2-hydroxymethylpyrrolidine (0.80 g, 4.00 mmol) and phenol (1.13 g, 12.00 mmol) provided 0.99 g (89%) of the title compound. MS (DCI, NH3): 278 (MH+).