Lithium hydroxide, monohydrate → HCID 70227896, compound

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Reaction Steps

The product from Example 1300C (46.5 mg, 0.08 mmol) was allowed to react with lithium hydroxide monohydrate (4 mg, 0.08 mmol) in a manner similar to that described in Example 608E to afford the title compound. 1H NMR (DMSO-d6, 300 MHz) δ 0.75-0.88 (m, 2H), 1.08-1.38 (m, 10H), 1.53-2.01 (m, 14H), 2.15 (m, 1H), 2.39-2.49 (m, 4H), 2.57-2.75 (m, 2H), 3.32 (d, partially buried under water peak 2H), 3.66 (m, 1H), 6.86 (d, J=6 Hz, 1H), 6.95 (m, 1H), 7.12-7.26 (m, 4H), 7.47 (d, J=8 Hz, 1H); MS (APCI(−)) m/z: (M−H)− 554; Anal. Calcd for C32H44LiNO3S2.1.75 H2O: C, 64.78; H, 8.07; N, 2.36. Found: C, 64.75; H, 7.40; N, 2.20.

Provenance & Evidence