関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Acetic Anhydride | HCID 7918 | — |
| 反応物 | Ethyl Acetate | HCID 8857 | — |
| 反応物 | Magnesium Acetate | HCID 8896 | — |
| 反応物 | N-acetoacetylaspartic acid | HCID 13334672 | — |
| 溶媒 | Methanol | HCID 887 | — |
| 生成物 | N-acetoacetyl-L-aspartic anhydride | HCID 13334674 | — |
反応手順
2.17 parts of N-acetoacetyl-L-aspartic acid, 1.02 parts by volume of acetic anhydride, and 0.014 parts of magnesium acetate were mixed with 40 parts by volume of ethyl acetate and heated at 55±2° C. under nitrogen for 24 hours. 30 parts by volume of methanol was added and the mixture stirred at ambient temperatures for 5 hours. HPLC analysis of the resulting solution showed only 0.5% unreacted N-acetoacetyl-L-aspartic acid.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US04440677 |
|---|
| 出典データセット | uspto-grants-1984_04 |
|---|
| ORD ID | ord-aded7f4057e441d5be9e893efb22e00a |
|---|
| 出典メモ | uspto-grants-1984_04 |
|---|
