L-Phenylalanine, methyl ester → N-acetoacetyl-alpha-L-aspartyl-L-phenylalanine

HRID 325276Notes

Reaction equation

HRID 325276 reaction equation
[C:1]([NH:7][C@@H:8]1[C:13](=[O:14])[O:12][C:10](=[O:11])[CH2:9]1)(=[O:6])[CH2:2][C:3]([CH3:5])=[O:4].C[O:16][C:17](=[O:27])[C@H:18]([CH2:20][C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1)[NH2:19]>>[C:1]([NH:7][C@H:8]([C:13]([NH:19][C@H:18]([C:17]([OH:27])=[O:16])[CH2:20][C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1)=[O:14])[CH2:9][C:10](=[O:11])[OH:12])(=[O:6])[CH2:2][C:3]([CH3:5])=[O:4]

Participants

3

Reactant 2

HCID 736234L-Phenylalanine, methyl esterHCID 13334674N-acetoacetyl-L-aspartic anhydride

Product 1

HCID 22826161N-acetoacetyl-alpha-L-aspartyl-L-phenylalanine

Procedure

reacting the resulting N-acetoacetyl-L-aspartic acid anhydride with L-phenylalanine methyl ester to form N-acetoacetyl-α-L-aspartyl-L-phenylalanine and

Sources & evidence

ORD record
ord-94dac047a3b24ac0bf90ede38ee702ba
Source dataset
uspto-grants-1984_04
Patent number
US04440677

Reaction notes

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