Diethyl Ether → 74137-64-7

Participants

Reaction Steps

Ergocristinine (1.25 g; 0.05 mmoles) was dissolved in absolute ethanol (25 ml), containing methanesulfonic acid (0.15 ml; 2.31 mmoles). After clarifying, the solution was slowly poured into absolute diethylether (350 ml) while stirring. The precipitated salt was filtered off and dried in vacuo. Ergocristinine methanesulfonate (1.40 g; 96.4% of the theory) with a melting point of 170°-180° C. was obtained.

Provenance & Evidence