Pyridine → HCID 23460501, compound

HRID 325293Notes

Reaction equation

HRID 325293 reaction equation
[Br:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[N:8]=[C:7]([CH3:12])[C:6]1[C:13](O[C:16](=[O:17])[C:5]2=1)=[O:14].[N:18]1C=CC=C[CH:19]=1>>[O:17]=[C:16]1[C:5]2[C:4]3[CH:3]=[C:2]([Br:1])[CH:11]=[CH:10][C:9]=3[N:8]=[C:7]([CH3:12])[C:6]=2[C:13](=[O:14])[N:18]1[CH3:19]

Participants

3

Reactant 2

HCID 1049PyridineHCID 15154343HCID 15154343, compound

Product 1

HCID 23460501HCID 23460501, compound

Procedure

To 350 ml of dry pyridine was added 14.7 g of the anhydride (ix) in a 3-neck flask with reflux condenser, drying tube, magnetic stirrer and a thermometer. The flask was cooled with an ice/H2O bath and dry reagent grade CH3NH2 was passed into the mixture. The flask was then allowed to warm up to room temperature and refluxed for 20 hours.

Workup

  1. temperaturewith reflux condenser
  2. customdrying tube, magnetic stirrer
  3. temperatureThe flask was cooled with an ice/H2O bath
  4. temperaturerefluxed for 20 hours

Sources & evidence

ORD record
ord-69e5bb21900d4ca8bf142e50528c64ad
Source dataset
uspto-grants-1984_04
Patent number
US04440768

Reaction notes

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