4-(Methylthio)thieno[2,3-d]pyrimidine-6-carbaldehyde → 4-(Methylthio)thieno[3,2-d]pyrimidine-6-carbaldehyde

HRID 32530Notes

Reaction equation

HRID 32530 reaction equation
CSC1C2C=C([CH:12]=[O:13])SC=2N=CN=1.[CH3:14][S:15][C:16]1[C:17]2[S:24][CH:23]=[CH:22][C:18]=2[N:19]=[CH:20][N:21]=1>>[CH3:14][S:15][C:16]1[C:17]2[S:24][C:23]([CH:12]=[O:13])=[CH:22][C:18]=2[N:19]=[CH:20][N:21]=1

Participants

3

Reactant 2

HCID 179658594-(Methylthio)thieno[2,3-d]pyrimidine-6-carbaldehydeHCID 179658614-(Methylsulfanyl)thieno[3,2-d]pyrimidine2×

Product 1

HCID 226492824-(Methylthio)thieno[3,2-d]pyrimidine-6-carbaldehyde

Procedure

The title compound was prepared by a similar process to that described for Intermediate 15 but using 4-(methylthio)thieno[3,2-d]pyrimidine (intermediate 20) in place of 4-(methylthio)thieno[2,3-d]pyrimidine. Yellow solid (434 mg, 38%);

Sources & evidence

ORD record
ord-22b10047e56746da892f55fe47c45d21
Source dataset
uspto-grants-2008_09
Patent number
US07427616B2

Reaction notes

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