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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 32538Generated: October 25, 2026

4-Methoxybenzylamine → 5-(Dimethoxymethyl)-1-(4-methoxybenzyl)-4-phenyl-1H-imidazole

https://huagongshe.com/reaction/32538

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-MethoxybenzylamineHCID 75452—
ReactantAcetaldehyde, 2,2-dimethoxy-HCID 162650—
Reactant(1-Methyl-4-phenyl-1H-imidazol-5-YL)methanolHCID 17965886—
Product5-(Dimethoxymethyl)-1-(4-methoxybenzyl)-4-phenyl-1H-imidazoleHCID 17965808—

Reaction Steps

The title compound was prepared by a similar process to that described for preparation of Intermediate 1, except that 4-methoxybenzylamine was used in place of methylamine and dimethoxyacetaldehyde in place of glycolaldehyde. Colourless oil (1.5 g, 74%);

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07427616B2
Source datasetuspto-grants-2008_09
ORD IDord-4ba0fc3093b642a380e91fa81ffc746d
Source noteuspto-grants-2008_09