反应详情

N-(2-Acetylthio-3-methoxybenzoyl)-N-cyclopentylglycine (4.4 g, 12.5 mmol) was stirred with excess sodium hydroxide solution for 2 hours at 25° C., then acidified and extracted with ethyl acetate. The extract was washed with water and brine, then dried and concentrated. The amorphous product was obtained by column chromatography of the residue.

1. extractionextracted with ethyl acetate
2. washThe extract was washed with water and brine
3. customdried
4. concentrationconcentrated
5. customThe amorphous product was obtained by column chromatography of the residue