3-Amino-4-methoxy-1,2,5-thiadiazole 1-oxide → HCID 23312508, compound

Participants

Reaction Steps

When a methanolic solution of 3-(6-dimethylaminomethyl-2-pyridyloxy)propylamine [prepared according to published United Kingdom Patent Application No. 2,098,988] is reacted with 3-amino-4-methoxy-1,2,5-thiadiazole 1-oxide according to the general procedure described in U.S. Pat. No. 4,374,248, PG,42 and the resulting 3-amino-4-[3-(6-piperidinomethyl-2-pyridyloxy)-propylamino]-1,2,5-thiadiazole 1-oxide is reacted according to the general procedure described in Example 3, the title compound is thereby produced.

Provenance & Evidence