N-(3,4-dimethoxybenzyl)-N-[thieno[2,3-d]pyrimidin-6-ylmethylidene]amine → HCID 17965874, compound

HRID 32560Notes

Reaction equation

HRID 32560 reaction equation
[CH2:1]([N:8]=[CH:9][C:10]1[S:18][C:13]2[N:14]=[CH:15][N:16]=[CH:17][C:12]=2[CH:11]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.CO[C:21]1[CH:22]=[C:23]([CH:36]=[CH:37][C:38]=1OC)[CH2:24][N:25]=[CH:26]C1SC2N=CN=CC=2C=1>>[CH2:1]([N:8]1[C:9]([C:10]2[S:18][C:13]3[N:14]=[CH:15][N:16]=[CH:17][C:12]=3[CH:11]=2)=[C:24]([C:23]2[CH:36]=[CH:37][CH:38]=[CH:21][CH:22]=2)[N:25]=[CH:26]1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 17965764N-(3,4-dimethoxybenzyl)-N-[thieno[2,3-d]pyrimidin-6-ylmethylidene]amineHCID 69194866N-benzyl-N-[thieno[2,3-d]pyrimidin-6-ylmethylidene]amine2×

Product 1

HCID 17965874HCID 17965874, compound

Procedure

The title compound was prepared by a similar process to that described for Example 6 but using N-benzyl-N-[thieno[2,3-d]pyrimidin-6-ylmethylidene]amine (Intermediate 51) in place of N-(3,4Dimethoxybenzyl)-N-[thieno[2,3-d]pyrimidin-6-ylmethylidene]amine (intermediate 14). Pale yellow solid (26 mg, 26%);

Sources & evidence

ORD record
ord-3da1917e289d457591201c37f59a2ca0
Source dataset
uspto-grants-2008_09
Patent number
US07427616B2

Reaction notes

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