Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | Enoxacin hydrochloride | HCID 12901163 | — |
| Solvent | Water | HCID 962 | — |
| Product | Enoxacin | HCID 3229 | — |
Reaction Steps
About 10 g of AT-2266.hydrochloride was dissolved to hot water (about 70° C.) and the solution was neutralized with 15% aqueous solution of sodium hydroxide which was warmed to 70° C. previously. The precipitate was collected by filtration and dried at 70° to 80° C. for elimination of adhering water to give the AT-2266.sesquihydrate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US04442101 |
|---|
| Source dataset | uspto-grants-1984_04 |
|---|
| ORD ID | ord-b477c5e573b74f0f821d8fb612284fb3 |
|---|
| Source note | uspto-grants-1984_04 |
|---|
