Formaldehyde → HCID 178488814, compound

HRID 325636Notes

Reaction equation

HRID 325636 reaction equation
[OH:1][C:2]1[C:11]2[C:6](=[C:7]([O:12][CH3:13])[CH:8]=[CH:9][CH:10]=2)[N:5]=[CH:4][CH:3]=1.[CH2:14]=[O:15]>[OH-].[Na+]>[OH:1][C:2]1[C:11]2[C:6](=[C:7]([O:12][CH3:13])[CH:8]=[CH:9][CH:10]=2)[N:5]=[CH:4][C:3]=1[CH2:14][OH:15]

Participants

4

Reactant 2

HCID 712FormaldehydeHCID 178488809HCID 178488809, compound

Product 1

HCID 178488814HCID 178488814, compound

Reagents, catalysts & solvents 1

HCID 14798Sodium HydroxideSolvent

Procedure

4-Hydroxy-8-methoxyquinoline was reacted with formaldehyde in aqueous sodium hydroxide to give the novel compound 4-hydroxy-3-hydroxymethyl-8-methoxyquinoline, m.p. >350°.

Sources & evidence

ORD record
ord-a59fb586fb2f4a6dbbac40d1b6551688
Source dataset
uspto-grants-1984_04
Patent number
US04442109

Reaction notes

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