Formaldehyde → HCID 178435555, compound

HRID 325643Notes

Reaction equation

HRID 325643 reaction equation
[CH2:1]([C:3]1[CH:12]=[C:11]2[C:6]([C:7]([OH:13])=[CH:8][CH:9]=[N:10]2)=[CH:5][CH:4]=1)[CH3:2].[CH2:14]=[O:15]>[OH-].[Na+]>[CH2:1]([C:3]1[CH:12]=[C:11]2[C:6]([C:7]([OH:13])=[C:8]([CH2:14][OH:15])[CH:9]=[N:10]2)=[CH:5][CH:4]=1)[CH3:2]

Participants

4

Reactant 2

HCID 712FormaldehydeHCID 178435553HCID 178435553, compound

Product 1

HCID 178435555HCID 178435555, compound

Reagents, catalysts & solvents 1

HCID 14798Sodium HydroxideSolvent

Procedure

7-Ethyl-4-hydroxyquinoline was reacted with 40% aqueous formaldehyde in aqueous sodium hydroxide to give the novel compound 7-ethyl-4-hydroxy-3-hydroxymethylquinoline, m.p. 180°-182°.

Sources & evidence

ORD record
ord-421b8072d27442b6bf2cc1b867b3892b
Source dataset
uspto-grants-1984_04
Patent number
US04442109

Reaction notes

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