Potassium Hydroxide → HCID 23677908, compound

HRID 325733Notes

Reaction equation

HRID 325733 reaction equation
C(N1C(C(OCC)=O)=NNN1)C1C=CC=CC=1.[CH2:18]([N:25]1[N:29]=[N:28][C:27]([C:30]([O:32]CC)=[O:31])=[N:26]1)[C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1.S1(CCCC1)(=O)=O.[OH-].[K+:43]>C(O)C.O>[CH2:18]([N:25]1[N:29]=[N:28][C:27]([C:30]([O-:32])=[O:31])=[N:26]1)[C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1.[K+:43]

Participants

7

Reactant 4

HCID 14797Potassium HydroxideHCID 31347SulfolaneHCID 13596242HCID 13596242, compoundHCID 20463868HCID 20463868, compound

Product 1

HCID 23677908HCID 23677908, compound

Reagents, catalysts & solvents 2

HCID 702EthanolSolventHCID 962WaterSolvent

Procedure

A mixture of ethyl 1-benzyl-2H-tetrazole-5-carboxylate and ethyl 2-benzyl-2H-tetrazole-5-carboxylate (7 g; prepared as described below and still containing a little sulpholane) was dissolved in hot ethanol (100 ml) and the hot solution was treated with a solution of potassium hydroxide (2.7 g) in water (8 ml). The white solid which separated was filtered off from the hot solution and washed with ethanol to give potassium 2-benzyl-2H-tetrazole-5-carboxylate (4.64 g), m.p. 264°-267° C. [The pure salt, obtained as a hemihydrate after recrystallisation from water, had a melting point of 272°-273° C.]

Workup

  1. customprepared
  2. customThe white solid which separated
  3. filtrationwas filtered off from the hot solution
  4. washwashed with ethanol

Sources & evidence

ORD record
ord-1c4a0bd1c6dc4a18bc9093e14f4f0f00
Source dataset
uspto-grants-1984_04
Patent number
US04442115

Reaction notes

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