反应详情

The imine from cyclohexanone and benzylamine was prepared in benzene in the normal way. To this imine (37.4 g; 0.2 mole) was added phosphorous acid (16.4 g; 0.2 mole) and the mixture stirred while heating. The reaction mixture became a homogeneous liquid at 70° and at 95°-100° a vigorous reaction took place. After keeping at 110°-130° for 30 minutes the mixture was cooled and diluted with water. Basification with NaOH and extraction with benzene gave after evaporation of the solvent N-benzylcyclohexylamine (80%). Distillation gave pure N-benzylcyclohexylamine bp 120°-125°/3 mm.

1. temperaturewhile heating
2. customat 70°
3. customat 95°-100° a vigorous reaction
4. temperaturethe mixture was cooled
5. extractionBasification with NaOH and extraction with benzene
6. customgave
7. customafter evaporation of the solvent N-benzylcyclohexylamine (80%)
8. distillationDistillation