HuagongsheHuagongshe Chemistry Print Report · For research reference only
methyl 3-isothiocyanato-4-methylthiophene-2-carboxylate → HCID 135966604, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | methyl 3-isothiocyanato-4-methylthiophene-2-carboxylate | HCID 2777569 | — |
| Reactant | 81321-14-4 | HCID 2807920 | — |
| Reactant | HCID 54288711 | HCID 54288711 | — |
| Product | HCID 135966604 | HCID 135966604 | — |
Reaction Steps
The starting material can be prepared in an analogous manner to Example 1 starting from 3-amino-4-methyl-2-thiophenecarboxylic acid methyl ester hydrochloride via 4-methyl-3-isothiocyanato-2-thiophenecarboxylic acid methyl ester (70 g, melting point 227°-228°) and 1,4-dihydro-7-methyl-4-oxo-2-thioxothieno[3,2-d]pyrimidine-3(2H)-acetic acid methyl ester (69 g, melting point 227°-228°); yield 68.9 g, melting point 131°-132°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04442289 |
| Source dataset | uspto-grants-1984_04 |
| ORD ID | ord-1464e36632d4453884f5ffa2e8cf9d2f |
| Source note | uspto-grants-1984_04 |