HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-[(4-bromophenyl)(toluene-4-sulfonyl)methyl]formamide → a-Tosyl-(4-bromobenzyl) isocyanide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-[(4-bromophenyl)(toluene-4-sulfonyl)methyl]formamide | HCID 12181677 | — |
| Reactant | (3-Iodophenyl)(isocyano)methyl 4-methylphenyl sulfone | HCID 17965763 | — |
| Reactant | {(3-Iodophenyl)[(4-methylphenyl)sulfonyl]methyl}formamide | HCID 85929703 | — |
| Product | a-Tosyl-(4-bromobenzyl) isocyanide | HCID 2771757 | — |
Reaction Steps
The title compound was prepared by a similar process to that described for Intermediate 53 but using {(4-bromophenyl)[(4-methylphenyl)sulfonyl]methyl}formamide (Intermediate 65) in place of {(3-iodophenyl)[(4-methylphenyl)sulfonyl]methyl}formamide (Intermediate 52). Brown solid (3.1 g, 29%);
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07427616B2 |
| Source dataset | uspto-grants-2008_09 |
| ORD ID | ord-92deb0654af94aca83286e2e2e8a1661 |
| Source note | uspto-grants-2008_09 |