Dichloromethane → HCID 20464124, compound

Participants

Reaction Steps

A solution of 3.2 g (0.005 moles) of 1-[3',5'-bis-(4-pivaloyloxybenzoyloxy)phenyl]-2-bromoethanol and 1.1 g (0.015 moles) of t-butylamine in 100 ml of methylene chloride was boiled under reflux for 18 hrs. After evaporation to dryness, diethyl ether was added to the residue. The precipitated t-butylamino hydrobromide (0.2 g) was filtered off and the filtrate was then acidified with ethanolic hydrochloric acid. HPLC analysis of this solution showed the presence of the title compound as compared with an authentic sample. ##STR63## The 1-[3',5'-bis-(4-pivaloyloxybenzoyloxy)phenyl]-2-bromoethanol which was used as starting material was prepared as follows.

Provenance & Evidence