反应详情

A solution of 7-acetylthio-2-propylheptanoic acid (0.8 g) in 5 N methanolic ammonia (50 ml) was stirred for 2 hours at ambient temperature in an argon atmosphere and concentrated to dryness under reduced pressure. The residue was dissolved in a small amount of a mixture of water and methanol and passed through a column of ion-exchange resin (Dowex 50W, H+ type). The eluate with a mixture of water and methanol was concentrated to dryness under reduced pressure to give semisolid of 7-mercapto-2-propylheptanoic acid (0.4 g).

1. concentrationconcentrated to dryness under reduced pressure
2. dissolutionThe residue was dissolved in a small amount of a mixture of water and methanol
3. additionThe eluate with a mixture of water and methanol
4. concentrationwas concentrated to dryness under reduced pressure