Hydrochloric Acid → HCID 13314917, compound

Participants

Reaction Steps

To 1.53 g (0.01 mole) of pivalyloxymethyl chloride dissolved in 30 ml of THF was added 1.14 g (0.01 mole) of 1-methyl-2-mercaptoimidazole. The clear yellow solution that resulted was stirred at room temperature overnight. The solution was concentrated to give a glass which was triturated twice with 100 ml of ether. The suspension was filtered and the residue was dried to give 1.85 g (mp 128°-132°, 67% yield) of the desired product as its hydrochloride. IR (KBr) 2800-2200 cm-1 ; (broad, s) (N+H), 1730 cm-1 (s) (C=O) and 1870 and 1820 cm-1 ; 1H NMR (CDCl3) δ7.60 (broad s, 2, N--CH=CH--N), 5.85 (s, 2, CO2CH2S), 3.57 (s, 3, N--CH3) and 1.18 (s, 9, (CH3)3C).

Provenance & Evidence