反应详情

A mixture of 1-[1-(3,4-dichlorophenyl)cyclobutyl]butan-2-one (4.3 g) prepared as described above, hydroxylamine sulphate (2.65 g), sodium acetate (4.0 g), industrial methylated spirit (56 ml) and water (23 ml) was stirred at ambient temperature for sixteen hours. The reaction mixture was extracted with ether. The ether extract was washed with water, dried and evaporated to give a solid which was recrystallised from petroleum ether (b.p. 80°-100° C.) to give 1-[1-(3,4-dichlorophenyl)cyclobutyl]butan-2-one oxime (m.p. 106°-110° C.).

1. customprepared
2. extractionThe reaction mixture was extracted with ether
3. extractionThe ether extract
4. washwas washed with water
5. customdried
6. customevaporated
7. customto give a solid which
8. customwas recrystallised from petroleum ether (b.p. 80°-100° C.)