7-(Methylthio)[1,3]thiazolo[5,4-d]pyrimidine-2-carbaldehyde → 2-(1-ethyl-4-phenyl-1H-imidazol-5-yl)-7-(methylthio)[1,3]thiazolo[5,4-d]pyrimidine

Participants

Role	Name	HCID	Charge
Reactant	7-(Methylthio)[1,3]thiazolo[5,4-d]pyrimidine-2-carbaldehyde	HCID 17965798	—
Reactant	4-(Methylthio)thieno[2,3-d]pyrimidine-6-carbaldehyde	HCID 17965859	—
Reactant	6-(1-ethyl-4-phenyl-1H-imidazol-5-yl)-4-(methylthio)thieno[2,3-d]pyrimidine	HCID 69194927	—
Product	2-(1-ethyl-4-phenyl-1H-imidazol-5-yl)-7-(methylthio)[1,3]thiazolo[5,4-d]pyrimidine	HCID 69196002	—

Reaction Steps

The title compound was prepared by a similar process to that described for Intermediate 70 but using 7-(methylthio)[1,3]thiazolo[5,4-d]pyrimidine-2-carbaldehyde (Intermediate 77) in place of 4-(methylthio)thieno[2,3-d]pyrimidine-6-carbaldehyde (Intermediate 15). Yellow solid (103 mg, 58%);

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07427616B2
Source dataset	uspto-grants-2008_09
ORD ID	ord-483635de726e4108b10d90ce9663f9f8
Source note	uspto-grants-2008_09