HCID 20458508, compound → HCID 54296925, compound

HRID 325955Notes

Reaction equation

HRID 325955 reaction equation
[C:1]1([S:11]([NH:14][CH2:15][CH2:16][C:17]2[CH:29]=[CH:28][C:20]([CH:21]=[CH:22][C:23]([O:25]CC)=[O:24])=[CH:19][CH:18]=2)(=[O:13])=[O:12])[C:10]2[C:5](=CC=CC=2)[CH:4]=[CH:3][CH:2]=1.Cl.NCCC1C=CC(C=CC(OCC)=O)=CC=1.C1(OS([Cl:61])(=O)=O)C2C(=CC=CC=2)C=CC=1>>[Cl:61][C:4]1[CH:5]=[CH:10][C:1]([S:11]([NH:14][CH2:15][CH2:16][C:17]2[CH:29]=[CH:28][C:20]([CH:21]=[CH:22][C:23]([OH:25])=[O:24])=[CH:19][CH:18]=2)(=[O:13])=[O:12])=[CH:2][CH:3]=1

Participants

4

Reactant 3

HCID 20458508HCID 20458508, compoundHCID 54097494HCID 54097494, compoundHCID 70512638Ethyl 3-[4-(2-aminoethyl)phenyl]prop-2-enoate--hydrogen chloride (1/1)

Product 1

HCID 54296925HCID 54296925, compoundYield 88%

Procedure

ethyl 4-[2-(1-naphthylsulphonamido)-ethyl]-cinnamate from ethyl 4-(2-aminoethyl)-cinnamate hydrochloride and 1-napthylsulphochloride; m.p. 85°-86° C. (recrystallized from ethanol); yield 88% of theory, and therefrom by hydrolysis

Workup

  1. customm.p. 85°-86° C. (recrystallized from ethanol)
  2. customyield 88% of theory, and therefrom by hydrolysis

Sources & evidence

ORD record
ord-98923db8733a40e1971598224fcccefc
Source dataset
uspto-grants-1984_04
Patent number
US04443477

Reaction notes

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