HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(4-Fluorobenzoyl)propyl chloride → alpha-Phenyl-4-(5-fluoro-1-naphthalenyloxy)-1-piperidinepropanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(4-Fluorobenzoyl)propyl chloride | HCID 19750 | — |
| Reactant | 3-Bromo-1-phenylpropan-1-OL | HCID 13561298 | — |
| Reactant | 4-(5-Fluoro-1-naphthalenyloxy)piperidine | HCID 20463197 | — |
| Reactant | (1-Methyl-2-naphthalenyloxy)piperidine | HCID 20463207 | — |
| Product | alpha-Phenyl-4-(5-fluoro-1-naphthalenyloxy)-1-piperidinepropanol | HCID 20463211 | — |
Reaction Steps
When in the procedure of Example 18, 4-(5-fluoro-1-naphthalenyloxy)piperidine is substituted for (1-methyl-2-naphthalenyloxy)piperidine and 3-bromo-1-phenylpropanol substituted for 4-chloro-1-(4-fluorophenyl)-1-butanone, α-phenyl-4-(5-fluoro-1-naphthalenyloxy)-1-piperidinepropanol is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04443462 |
| Source dataset | uspto-grants-1984_04 |
| ORD ID | ord-91c84d6ddcfe48a5ac999ccd7355912f |
| Source note | uspto-grants-1984_04 |