HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Phenylindole → N,N-Dimethylaniline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Phenylindole | HCID 13698 | — |
| Reactant | 6-(Dimethylamino)-3-(4-methoxyphenyl)-2-benzofuran-1(3H)-one | HCID 12389694 | — |
| Product | N,N-Dimethylaniline | HCID 949 | — |
| Product | HCID 12399043 | HCID 12399043 | — |
| Product | 3-[3-(Diethylamino)phenyl]-6-(dimethylamino)-2-benzofuran-1(3H)-one | HCID 20463586 | — |
Reaction Steps
Example 14 was repeated except that 29 g of 3-(p-methoxyphenyl)-6-dimethylaminophthalide and 19.5 g of 2-phenylindole were used, respectively, instead of 33 g of 3-(m-diethylaminophenyl)-6-dimethylaminophthalide and 13 g of dimethylaniline to obtain 24 g of 3-(p-methoxyphenyl)-3-(2-phenylindole-3-yl)-6-dimethylaminophthalide having the following structure whose m.p. was 224°-225° C. in the form of colourless crystals (Recrystallization from benzene-methanol). This compound becomes blue black on contact with silica gel. ##STR74##
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04443614 |
| Source dataset | uspto-grants-1984_04 |
| ORD ID | ord-96957aa4c31147d9b6b572f8da7c4615 |
| Source note | uspto-grants-1984_04 |