HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl chloroacetate → Ethyl chloroacetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl chloroacetate | HCID 7751 | — |
| Reactant | Ethyl Acetate | HCID 8857 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | Ethyl chloroacetate | HCID 7751 | — |
| Product | Diethyl Malonate | HCID 7761 | — |
Reaction Steps
As described in Example 1, but with 160 g of an 8.85% solution of Co2 (CO)8 in ethanol, 2.7 moles out of 4 moles of chloroacetic acid ethyl ester are reacted at 7.5 at. CO and 55° C. in 51/4 hours. 400 g of malonic acid diethyl ester is obtained (93% yield) and 3.5 g of acetic acid ethyl ester plus 160 g of chloroacetic acid ethyl ester.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04443624 |
| Source dataset | uspto-grants-1984_04 |
| ORD ID | ord-29e46135d35d4e749c018a018dfc4f90 |
| Source note | uspto-grants-1984_04 |