2-Chloroquinoline → HCID 12884165, compound

HRID 326036Notes

Reaction equation

HRID 326036 reaction equation
Cl[C:2]1[CH:11]=[CH:10][C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[N:3]=1.[OH:12][C:13]1[CH:25]=[CH:24][C:16]([O:17][CH:18]([CH3:23])[C:19]([O:21][CH3:22])=[O:20])=[CH:15][CH:14]=1>>[CH3:22][O:21][C:19](=[O:20])[CH:18]([O:17][C:16]1[CH:24]=[CH:25][C:13]([O:12][C:2]2[CH:11]=[CH:10][C:9]3[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=3)[N:3]=2)=[CH:14][CH:15]=1)[CH3:23]

Participants

3

Reactant 2

HCID 119282-ChloroquinolineHCID 366926Propanoic acid, 2-(4-hydroxyphenoxy)-, methyl ester

Product 1

HCID 12884165HCID 12884165, compound

Procedure

Methyl-2-[4-(2-quinolinyloxy)phenoxy]propionate (24) was prepared from 2-chloroquinoline and methyl 2-(4-hydroxyphenoxy)propionate following essentially the same procedure as that described in Example 1. The compound had a melting point of 95°-100° C.

Sources & evidence

ORD record
ord-b533974f426c4f23bf267e06a05c4172
Source dataset
uspto-grants-1984_04
Patent number
US04444584

Reaction notes

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