HuagongsheHuagongshe Chemistry Print Report · For research reference only
Caprolactam → 1-Pentylazepan-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Caprolactam | HCID 7768 | — |
| Reactant | 1-Bromopentane | HCID 8057 | — |
| Reactant | Sodium hydride | HCID 24758 | — |
| Product | 1-Pentylazepan-2-one | HCID 12833261 | 87% |
Reaction Steps
Following example 8 and using water condenser from the start of the reaction, 10 g of 50% sodium hydride-mineral oil dispersion (5 g NaH, 0.21 M), 20 g (0.177 M) of azacycloheptan-2-one and 30.2 g (0.2 M) of 1-bromopentane on 18 hr. reflux gave 23.3 g (87%) of colorless product; b.p. 110°-115°/0.3 mm.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04444762 |
| Source dataset | uspto-grants-1984_04 |
| ORD ID | ord-d772fd4a24d5442f84e803b21de08f44 |
| Source note | uspto-grants-1984_04 |