HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloroaniline → 1-(2-Chlorophenyl)pyrrolidin-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloroaniline | HCID 7240 | — |
| Reactant | Gamma-Butyrolactone | HCID 7302 | — |
| Product | 1-(2-Chlorophenyl)pyrrolidin-2-one | HCID 4140553 | 25.4% |
Reaction Steps
Following example 19, 12.57 g (0.1 M) of 2-chloroaniline and 9.5 g (0.11 M) of γ-butyrolactone were heated for 48 hours. The excess starging materials were removed at 50°-80°/0.3 mm. Distillation of the residue gave 4.9 g (25%) of product (45% based on recovered 2-chloroaniline); b.p. 150°-155°/0.3-0.4 mm.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04444762 |
| Source dataset | uspto-grants-1984_04 |
| ORD ID | ord-71849b497ed64b28a9bdc539061ebc86 |
| Source note | uspto-grants-1984_04 |