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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 326091Generated: October 25, 2026

3-Amino-5-methyl-4H-1,2,4-triazole → 2-Methyl-7-(2-thienyl)[1,2,4]triazolo[1,5-a]pyrimidine

https://huagongshe.com/reaction/326091

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Amino-5-methyl-4H-1,2,4-triazoleHCID 234610—
Reactant3-(Dimethylamino)-1-(2-thienyl)-2-propen-1-oneHCID 602399—
Product2-Methyl-7-(2-thienyl)[1,2,4]triazolo[1,5-a]pyrimidineHCID 13309048—

Reaction Steps

By the procedure described in Example 5, 3-amino-5-methyl-1,2,4-triazole was reacted with 3-dimethylamino-1-(2-thienyl)-2-propene-1-one to give 1.05 g of the product of the Example as pale yellow needles, mp 184°-185° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04444774
Source datasetuspto-grants-1984_04
ORD IDord-cff7d3a55df6465dbab1fcc5f9c42364
Source noteuspto-grants-1984_04