HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Bromoethanol → methyl 3-(2-hydroxyethylsulfanyl)propanoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Bromoethanol | HCID 10898 | — |
| Reactant | Methyl 3-mercaptopropionate | HCID 18050 | — |
| Reactant | Sodium | HCID 5360545 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | methyl 3-(2-hydroxyethylsulfanyl)propanoate | HCID 220049 | — |
Reaction Steps
A solution of 2.3 g. sodium in 80 ml. methanol, which contains 12 g. methyl 3-mercaptopropionate and 12.5 g. 2-bromoethanol, is stirred under reflux for 4 hours. After evaporating, the residue is taken up in chloroform, filtered and evaporated. 16 g. Methyl 3-(2-hydroxyethylthio)-propionate are obtained in the form of an oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04444766 |
| Source dataset | uspto-grants-1984_04 |
| ORD ID | ord-6d2fd456924a463a92178ad5673e9e42 |
| Source note | uspto-grants-1984_04 |