HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclopropanecarboxaldehyde → [5-(7-amino[1,3]thiazolo[5,4-d]pyrimidin-2-yl)-1-methyl-4-phenyl-1H-imidazol-2-yl](cyclopropyl)methyl dimethylcarbamate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclopropanecarboxaldehyde | HCID 123114 | — |
| Reactant | [5-(7-Amino[1,3]thiazolo[5,4-d]pyrimidin-2-yl)-1-methyl-4-phenyl-1H-imidazol-2-yl](phenyl)methyl dimethylcarbamate | HCID 69197371 | — |
| Product | [5-(7-amino[1,3]thiazolo[5,4-d]pyrimidin-2-yl)-1-methyl-4-phenyl-1H-imidazol-2-yl](cyclopropyl)methyl dimethylcarbamate | HCID 69196442 | — |
Reaction Steps
The title compound was prepared by a similar process to that described for Intermediate 97 but using cyclopropanecarboxaldehyde in place of benzaldehyde. Colourless gum (14 mg, 68%);
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07427616B2 |
| Source dataset | uspto-grants-2008_09 |
| ORD ID | ord-62ff8a8fefb74dbfb45c5961c9d8ad50 |
| Source note | uspto-grants-2008_09 |