HuagongsheHuagongshe Chemistry Print Report · For research reference only
Penicillin G → Phenylacetic Acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Penicillin G | HCID 5904 | — |
| Reactant | Butanediol | HCID 165788 | — |
| Product | Phenylacetic Acid | HCID 999 | — |
Reaction Steps
A solution of 40 mM of 6 APA and 200 mM of phenylacetic acid in 50% butanediol/50% acetate 50 mM is prepared at a pH of 6.5. The column is thermostatized at 4° C. The rest of the conditions are as in example 1. In these conditions, the degree of conversion of 6 APA to penicillin G is higher than 85%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05268271 |
| Source dataset | uspto-grants-1993_12 |
| ORD ID | ord-7ff2fb9dfe45419392a7bf161f6f47bf |
| Source note | uspto-grants-1993_12 |