反应详情

6.5 g of phosgene are dissolved in 60 ml of chloroform. 1.45 g of the hydrazide prepared in step A in 40 ml of chloroform are added dropwise and the mixture is refluxed for 4 hours. It is evaporated and the residue is taken up with DCM, washed with water, dried over sodium sulfate, filtered and evaporated to give 1.48 g of the expected product.

1. temperaturethe mixture is refluxed for 4 hours
2. customIt is evaporated
3. washwashed with water
4. dry with materialdried over sodium sulfate
5. filtrationfiltered
6. customevaporated